Danazol: What It Is and When It’s Used
If you’ve heard the name danazol, you’re probably wondering what it actually does. Danazol is a synthetic steroid that mimics some effects of male hormones. Doctors mainly prescribe it for conditions like endometriosis, certain breast cancers, and hereditary angioedema. It can also help with delayed puberty in boys. Knowing why it’s chosen helps you see if the benefits outweigh the risks.
How Danazol Works
Danazol works by reducing estrogen production and suppressing ovulation. Lower estrogen means less tissue buildup in endometriosis, which can ease painful periods. In breast cancer, it slows tumor growth by limiting hormone stimulation. For hereditary angioedema, the drug boosts C1‑inhibitor levels, cutting down swelling attacks. The key point is that danazol blocks hormones that fuel these problems.
Dosage, Safety & Common Side Effects
The usual dose starts low—often 100 mg once or twice a day—and your doctor may adjust it based on how you respond. Taking it with food can lessen stomach upset. Because danazol is a steroid, side effects are something to watch. You might notice weight gain, acne, voice changes, or mood swings. Some people develop liver enzyme changes, so regular blood tests are a must.
If you’re pregnant or planning to become pregnant, avoid danazol; it can harm the fetus. Women should use reliable birth control while on the drug. Men taking danazol may experience reduced sperm count, so discuss family plans with your doctor.
To keep risks low, follow the prescribed amount exactly and never stop abruptly—tapering off helps prevent hormone rebound. If side effects become bothersome, talk to your provider; they might lower the dose or switch you to another medication.
In summary, danazol can be a powerful tool for specific hormonal conditions, but it requires careful monitoring. Understanding how it works, the right dosage, and potential side effects puts you in control of your treatment decisions.
